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Gene Expression Literature Summary
Assay
Age
Immunohistochemistry (section)
13.5 DPC

38 matching records from 38 references.

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Tnnt2  troponin T2, cardiac   (Synonyms: cardiac TnT, cTnT, Tnt)
Results  Reference
1J:267310 Ai S, Yu X, Li Y, Peng Y, Li C, Yue Y, Tao G, Li C, Pu WT, He A, Divergent Requirements for EZH1 in Heart Development Versus Regeneration. Circ Res. 2017 Jul 7;121(2):106-112
1J:264380 Artap S, Manderfield LJ, Smith CL, Poleshko A, Aghajanian H, See K, Li L, Jain R, Epstein JA, Endocardial Hippo signaling regulates myocardial growth and cardiogenesis. Dev Biol. 2018 Aug 1;440(1):22-30
1J:328231 Astanina E, Doronzo G, Cora D, Neri F, Oliviero S, Genova T, Mussano F, Middonti E, Vallariello E, Cencioni C, Valdembri D, Serini G, Limana F, Foglio E, Ballabio A, Bussolino F, The TFEB-TGIF1 axis regulates EMT in mouse epicardial cells. Nat Commun. 2022 Sep 3;13(1):5191
1*J:335085 Baral K, D'amato G, Kuschel B, Bogan F, Jones BW, Large CL, Whatley JD, Red-Horse K, Sharma B, APJ+ cells in the SHF contribute to the cells of aorta and pulmonary trunk through APJ signaling. Dev Biol. 2023 Apr 8;498:77-86
1J:244630 Bardot E, Calderon D, Santoriello F, Han S, Cheung K, Jadhav B, Burtscher I, Artap S, Jain R, Epstein J, Lickert H, Gouon-Evans V, Sharp AJ, Dubois NC, Foxa2 identifies a cardiac progenitor population with ventricular differentiation potential. Nat Commun. 2017 Feb 14;8:14428
1J:257396 Carreira VS, Fan Y, Wang Q, Zhang X, Kurita H, Ko CI, Naticchioni M, Jiang M, Koch S, Medvedovic M, Xia Y, Rubinstein J, Puga A, Ah Receptor Signaling Controls the Expression of Cardiac Development and Homeostasis Genes. Toxicol Sci. 2015 Oct;147(2):425-35
1*J:86960 Darling DS, Stearman RP, Qi Y, Qiu MS, Feller JP, Expression of Zfhep/deltaEF1 protein in palate, neural progenitors, and differentiated neurons. Gene Expr Patterns. 2003 Dec;3(6):709-17
1J:313609 Diaz Del Moral S, Barrena S, Hernandez-Torres F, Aranega A, Villaescusa JM, Gomez Doblas JJ, Franco D, Jimenez-Navarro M, Munoz-Chapuli R, Carmona R, Deletion of the Wilms' Tumor Suppressor Gene in the Cardiac Troponin-T Lineage Reveals Novel Functions of WT1 in Heart Development. Front Cell Dev Biol. 2021;9:683861
1*J:319356 Dong K, Shen J, He X, Hu G, Wang L, Osman I, Bunting KM, Dixon-Melvin R, Zheng Z, Xin H, Xiang M, Vazdarjanova A, Fulton DJR, Zhou J, CARMN Is an Evolutionarily Conserved Smooth Muscle Cell-Specific LncRNA That Maintains Contractile Phenotype by Binding Myocardin. Circulation. 2021 Dec 7;144(23):1856-1875
1J:332240 Feng W, Bais A, He H, Rios C, Jiang S, Xu J, Chang C, Kostka D, Li G, Single-cell transcriptomic analysis identifies murine heart molecular features at embryonic and neonatal stages. Nat Commun. 2022 Dec 27;13(1):7960
1J:290729 Grundl M, Walz S, Hauf L, Schwab M, Werner KM, Spahr S, Schulte C, Maric HM, Ade CP, Gaubatz S, Interaction of YAP with the Myb-MuvB (MMB) complex defines a transcriptional program to promote the proliferation of cardiomyocytes. PLoS Genet. 2020 May;16(5):e1008818
1J:239361 Guimaraes-Camboa N, Stowe J, Aneas I, Sakabe N, Cattaneo P, Henderson L, Kilberg MS, Johnson RS, Chen J, McCulloch AD, Nobrega MA, Evans SM, Zambon AC, HIF1alpha Represses Cell Stress Pathways to Allow Proliferation of Hypoxic Fetal Cardiomyocytes. Dev Cell. 2015 Jun 08;33(5):507-21
1J:335098 Han F, Yang B, Chen Y, Liu L, Cheng X, Huang J, Zhou K, Zhang D, Xu E, Lai M, Lv B, Cheng H, Zhang H, Loss of GLTSCR1 causes congenital heart defects by regulating NPPA transcription. Angiogenesis. 2023 May;26(2):217-232
1J:257620 Hertig V, Matos-Nieves A, Garg V, Villeneuve L, Mamarbachi M, Caland L, Calderone A, Nestin expression is dynamically regulated in cardiomyocytes during embryogenesis. J Cell Physiol. 2018 Apr;233(4):3218-3229
1J:338840 Hertig V, Villeneuve L, Calderone A, Nestin identifies a subpopulation of rat ventricular fibroblasts and participates in cell migration. Am J Physiol Cell Physiol. 2023 Aug 1;325(2):C496-C508
1*J:315261 Hsu WH, Yu YR, Hsu SH, Yu WC, Chu YH, Chen YJ, Chen CM, You LR, The Wilms' tumor suppressor Wt1 regulates Coronin 1B expression in the epicardium. Exp Cell Res. 2013 Jun 10;319(10):1365-81
1J:334751 Jiang H, Bai L, Song S, Yin Q, Shi A, Zhou B, Lian H, Chen H, Xu CR, Wang Y, Nie Y, Hu S, EZH2 controls epicardial cell migration during heart development. Life Sci Alliance. 2023 Jun;6(6)
1J:342551 Kim EE, Shekhar A, Ramachandran J, Khodadadi-Jamayran A, Liu FY, Zhang J, Fishman GI, The transcription factor EBF1 non-cell-autonomously regulates cardiac growth and differentiation. Development. 2023 Nov 1;150(21)
1J:284141 Li D, Angermeier A, Wang J, Planar cell polarity signaling regulates polarized second heart field morphogenesis to promote both arterial and venous pole septation. Development. 2019 Oct 9;146(20):dev181719
1J:334567 Liu H, Duan R, He X, Qi J, Xing T, Wu Y, Zhou L, Wang L, Shao Y, Zhang F, Zhou H, Gu X, Lin B, Liu Y, Wang Y, Liu Y, Li L, Liang D, Chen YH, Endothelial deletion of PTBP1 disrupts ventricular chamber development. Nat Commun. 2023 Mar 31;14(1):1796
1J:344312 Liu H, Zhou R, Li S, Dong J, Fang Y, Luo Y, Su H, Lai B, Liang L, Zhang D, Zhang Y, Shyy JY, Zhou B, Yuan Z, Wang Y, Epigenetic repression of Cend1 by lysine-specific demethylase 1 is essential for murine heart development. iScience. 2024 Jan 19;27(1):108722
1J:259048 Liu X, Wang Y, Liu F, Zhang M, Song H, Zhou B, Lo CW, Tong S, Hu Z, Zhang Z, Wdpcp promotes epicardial EMT and epicardium-derived cell migration to facilitate coronary artery remodeling. Sci Signal. 2018 Feb 27;11(519)
1J:327414 Manivannan S, Mansfield C, Zhang X, Kodigepalli KM, Majumdar U, Garg V, Basu M, Single-cell transcriptomic profiling unveils dysregulation of cardiac progenitor cells and cardiomyocytes in a mouse model of maternal hyperglycemia. Commun Biol. 2022 Aug 15;5(1):820
1J:246542 Nakashima Y, Yanez DA, Touma M, Nakano H, Jaroszewicz A, Jordan MC, Pellegrini M, Roos KP, Nakano A, Nkx2-5 suppresses the proliferation of atrial myocytes and conduction system. Circ Res. 2014 Mar 28;114(7):1103-13
1J:230021 Peng Y, Song L, Zhao M, Harmelink C, Debenedittis P, Cui X, Wang Q, Jiao K, Critical roles of miRNA-mediated regulation of TGFbeta signalling during mouse cardiogenesis. Cardiovasc Res. 2014 Jul 15;103(2):258-67
1J:276877 Qu X, Harmelink C, Baldwin HS, Tie2 regulates endocardial sprouting and myocardial trabeculation. JCI Insight. 2019 May 21;5
1J:239700 Shekhar A, Lin X, Liu FY, Zhang J, Mo H, Bastarache L, Denny JC, Cox NJ, Delmar M, Roden DM, Fishman GI, Park DS, Transcription factor ETV1 is essential for rapid conduction in the heart. J Clin Invest. 2016 Dec 01;126(12):4444-4459
1J:338019 Shi W, Scialdone AP, Emerson JI, Mei L, Wasson LK, Davies HA, Seidman CE, Seidman JG, Cook JG, Conlon FL, Missense Mutation in Human CHD4 Causes Ventricular Noncompaction by Repressing ADAMTS1. Circ Res. 2023 Jun 23;133(1):48-67
1J:272602 Shigeta A, Huang V, Zuo J, Besada R, Nakashima Y, Lu Y, Ding Y, Pellegrini M, Kulkarni RP, Hsiai T, Deb A, Zhou B, Nakano H, Nakano A, Endocardially Derived Macrophages Are Essential for Valvular Remodeling. Dev Cell. 2019 Mar 11;48(5):617-630.e3
1J:338889 Siguero-Alvarez M, Salguero-Jimenez A, Grego-Bessa J, de la Barrera J, MacGrogan D, Prados B, Sanchez-Saez F, Pineiro-Sabaris R, Felipe-Medina N, Torroja C, Gomez MJ, Sabater-Molina M, Escriba R, Richaud-Patin I, Iglesias-Garcia O, Sbroggio M, Callejas S, O'Regan DP, McGurk KA, Dopazo A, Giovinazzo G, Ibanez B, Monserrat L, Perez-Pomares JM, Sanchez-Cabo F, Pendas AM, Raya A, Gimeno-Blanes JR, de la Pompa JL, A Human Hereditary Cardiomyopathy Shares a Genetic Substrate With Bicuspid Aortic Valve. Circulation. 2023 Jan 3;147(1):47-65
1J:217680 Trembley MA, Velasquez LS, de Mesy Bentley KL, Small EM, Myocardin-related transcription factors control the motility of epicardium-derived cells and the maturation of coronary vessels. Development. 2015 Jan 1;142(1):21-30
1J:175466 von Gise A, Zhou B, Honor LB, Ma Q, Petryk A, Pu WT, WT1 regulates epicardial epithelial to mesenchymal transition through beta-catenin and retinoic acid signaling pathways. Dev Biol. 2011 Aug 15;356(2):421-31
1*J:69158 Wang Q, Reiter RS, Huang QQ, Jin JP, Lin JJ, Comparative studies on the expression patterns of three troponin T genes during mouse development. Anat Rec. 2001 May 1;263(1):72-84
1J:278242 Xia M, Luo W, Jin H, Yang Z, HAND2-mediated epithelial maintenance and integrity in cardiac outflow tract morphogenesis. Development. 2019 Jul 4;146(13):dev177477
1*J:305946 Xu M, Yao J, Shi Y, Yi H, Zhao W, Lin X, Yang Z, The SRCAP chromatin remodeling complex promotes oxidative metabolism during prenatal heart development. Development. 2021 Apr 15;148(8):dev199026
1J:253740 Yan J, Zhang L, Sultana N, Oh JG, Wu B, Hajjar RJ, Zhou B, Cai CL, A series of robust genetic indicators for definitive identification of cardiomyocytes. J Mol Cell Cardiol. 2016 Aug;97:278-85
1J:290535 Zhang D, Li Y, Heims-Waldron D, Bezzerides V, Guatimosim S, Guo Y, Gu F, Zhou P, Lin Z, Ma Q, Liu J, Wang DZ, Pu WT, Mitochondrial Cardiomyopathy Caused by Elevated Reactive Oxygen Species and Impaired Cardiomyocyte Proliferation. Circ Res. 2018 Jan 5;122(1):74-87
1J:321836 Zhao K, Huang X, Zhao W, Lu B, Yang Z, LONP1-mediated mitochondrial quality control safeguards metabolic shifts in heart development. Development. 2022 Mar 15;149(6):dev200458

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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory